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ACROBiosystems Human CD133 Protein, His Tag (InsectCells)
Marke: ACROBiosystems CD3-H55H7-20ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Prominin-1 is also known as CD133, Antigen AC133, PROM1, PROML1 and MSTP061. Is used as marker for hematopoietic stem and progenitor cells (HSPC) for somatic stem cell isolation. May play a role in cell differentiation, proliferation and apoptosis . Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 97.2 kDa. The protein migrates as 80-95 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| NP_006008.1 | |
| 20 µg | |
| Gly 20 - His 865 | |
| CD133,PROM1,PROML1,Prominin-1,AC133 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / µg by the LAL method. | |
| Liquid | |
| >80% as determined by SDS-PAGE |
| 97.2 kDa | |
| Human CD133, His Tag (CD3-H55H7) is expressed from Baculovirus-Insect cells. It contains AA Gly 20 - His 865 (Accession # O43490-1). | |
| -70°C | |
| CD133 | |
| Human | |
| 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5 | |
| InsectCells | |
| Bio-Markers and CD Antigens |