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ACROBiosystems Biotinylated Human Integrin alpha 4 beta 1 (ITGA4&ITGB1) Heterodimer Protein, His, Avitag™&Tag Free
Biotinylated Protein
Marke: ACROBiosystems IT1-H82W1-200ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Integrins are transmembrane proteins that mediate interactions between adhesion molecules on adjacent cells and/or the extracellular matrix (ECM). Integrins have diverse roles in several biological processes including cell migration during development and wound healing, cell differentiation, and apoptosis. Their activities can also regulate the metastatic and invasive potential of tumor cells. Integrin alpha 4 beta 1(Alpha-4/beta-1) is receptors for fibronectin. Integrin alpha-4/beta-1 is a receptor for VCAM1 and recognizes the sequence Q-I-D-S in VCAM1.
Biotinylated Human ITGA4&ITGB1 Heterodimer Protein, His,Avitag&Tag Free, produced by co-expression of ITGA4 and ITGB1, has a calculated MW of 113.2 kDa (ITGA4) and 83.7 kDa (ITGB1). Subunit ITGA4 is fused with an acidic tail at the C-terminus and followedSpezifikation
| NP 000876.3 (ITGA4) and NP_002202.2 (ITGB1) | |
| 200 μg | |
| Tyr 34 - Thr 977 (ITGA4) and Gln 21 - Asp 728 (ITGB1) | |
| Integrin alpha 4 beta 1,ITGA4andITGB1 | |
| Precision Avi | |
| His Tag and Avi Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 113.2 kDa (ITGA4) and 83.7 kDa (ITGB1) | |
| Biotinylated Human ITGA4&ITGB1; Heterodimer Protein, His,AviTag&Tag; Free (IT1-H82W1) is expressed from human 293 cells (HEK293). It contains AA Tyr 34 - Thr 977 (ITGA4) and Gln 21 - Asp 728 (ITGB1) (Accession # P13612-1 (ITGA4) and P05556-1 (ITGB1)). | |
| -20°C | |
| Integrin alpha 4 beta 1 | |
| Human | |
| 50 mM Tris, 150 mM NaCl, pH7.5 | |
| HEK293 | |
| MABSol™ Biotin Labeled Proteins |