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ACROBiosystems FITC-Labeled Human PSMA / FOLH1 Protein, His Tag

Marke:  ACROBiosystems PSA-HF244-25ug

Weitere Details : Netto-Gewicht : 0.00010kg

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Artikelnummer. 16437989

  • 383.89 € / 25 Mikrogramm
Verfügbar ab: 09-04-2024
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Beschreibung

Beschreibung

Prostate-specific membrane antigen (PSMA) is also known as Folate hydrolase 1 (FOLH1), Glutamate carboxypeptidase 2 (GCP2), N-acetylated-alpha-linked acidic dipeptidase I (NAALAD1), which belongs to the peptidase M28 family and M28B subfamily. FOLH1 / PSMA is stable at pH greater than 6.5. FOLH1 / PSMA is a type II transmembrane zinc metallopeptidase that is most highly expressed in the nervous system, prostate, kidney, and small intestine. FOLH1 / GCP-2 is homodimer and binds 2 zinc ions per subunit, and required for NAALADase activity. The catalytic activity of PSMA involved in releasing of an unsubstituted, C-terminal glutamyl residue, typically from Ac-Asp-Glu or folylpoly – gamma - glutamates. FOLH1 / GCP-2 / PSMA has both folate hydrolase and N – acetylated – alpha – linked - acidic dipeptidase (NAALADase) activity and has a preference for tri-alpha-glutamate peptides. GCP-2 / PSMA involved in prostate tumor progression and also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 81.4 KDa. The protein migrates as 85-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_004467.1
25 μg
Lys 44 - Ala 750
FOLH1,PSMA,GIG27,FOLH,NAALAD1,PSM,NAALADase I,GCPII,FGCP
FITC
His Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
81.4 KDa
FITC-Labeled Human PSMA, His Tag (PSA-HF244) is expressed from human 293 cells (HEK293). It contains AA Lys 44 - Ala 750 (Accession # Q04609-1). It is the FITC labeled form of Human PSMA, His Tag (PSA-H52H3).
-20°C, avoid light
PSMA
Human
PBS, pH7.4
HEK293
Fluorescent labeled protein
Produktvorschläge

Produktvorschläge

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Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

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Sonderangebote

Sonderangebote