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ACROBiosystems Cynomolgus Siglec-15 / CD33L3 Protein, His Tag
Marke: ACROBiosystems SG5-C52H6-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Siglec-15 is a DAP12-associated immunoreceptor, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. Siglecs are cell surface proteins that bind sialic acid. They are found primarily on the surface of immune cells and are a subset of the I-type lectins. Siglec-15 consisting of immunoglobulin (Ig)-like domains, transmembrane domain and a short cytoplasmic tail. Siglec-15 is that recognizes sialylated glycans and regulates osteoclast differentiation. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.1 kDa. The protein migrates as 30-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
28.1 kDa | |
Cynomolgus Siglec-15, His Tag (SG5-C52H6) is expressed from human 293 cells (HEK293). It contains AA Phe 20 - Thr 263 (Accession # A0A2K5UY47-1). | |
-20°C | |
Siglec-15 | |
Cynomolgus Monkey | |
PBS with Arginine, pH7.4 | |
HEK293 | |
Other Recombinant Proteins |
100 μg | |
Phe 20 - Thr 263 | |
CD33 antigen-like 3,SIGLEC-15,CD33L3,sialic acid-binding Ig-like lectin 15,Siglec15,Siglec-15 | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>90% as determined by SDS-PAGE |