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ACROBiosystems Human B7-H4 Protein, Fc Tag, low endotoxin

low endotoxin

Marke:  ACROBiosystems B74-H5256-100ug

Weitere Details : Netto-Gewicht : 0.00010kg

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Artikelnummer. 16447189

  • 539.84 € / 100 Mikrogramm
Verfügbar ab: 09-04-2024
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Beschreibung

Beschreibung

V-set domain-containing T-cell activation inhibitor 1 (VTCN1) is also known as Immune costimulatory protein B7-H4, Protein B7S1, T-cell costimulatory molecule B7x, B7H4, which belongs to the immunoglobulin superfamily and BTN/MOG family. VTCN1 contains two Ig-like V-type (immunoglobulin-like) domains. The expression of VTCN1 is up-regulated by IL6 and IL10 and is inhibited by GM-CSF and IL4 on antigen-presenting cells (APCs). VTCN1 / B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. VTCN1 involved in promoting epithelial cell transformation.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 51.8 kDa. The protein migrates as 66-85 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_078902.2
100 μg
Phe 29 - Ala 258
B7-H4,VTCN1,B7S1,B7h0.5
Unconjugated
Fc Tag
Less than 0.01 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
51.8 kDa
Human B7-H4, Fc Tag, low endotoxin (B74-H5256) is expressed from human 293 cells (HEK293). It contains AA Phe 29 - Ala 258 (Accession # Q7Z7D3-1).
-20°C
B7-H4
Human
PBS, pH7.4
HEK293
Immune Checkpoint Proteins
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote