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ACROBiosystems Human IL-4 R alpha / CD124 Protein, Fc Tag
Marke: ACROBiosystems ILR-H5253-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
IL-4 R alpha is also known as IL4R, CD124, IL-4RA.This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE antibody production in B cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitis, asthma, or eczema. The binding of IL-4 or IL-13 to the IL-4 receptor on the surface of macrophages results in the alternative activation of those macrophages. Interleukin-4 receptor has been shown to interact with SHC1.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.4 kDa. The protein migrates as 60-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| NP_000409.1 | |
| 100 μg | |
| Met 26 - His 232 | |
| IL4R,CD124,IL4RA | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 50.4 kDa | |
| Human IL-4 R alpha, Fc Tag (ILR-H5253) is expressed from human 293 cells (HEK293). It contains AA Met 26 - His 232 (Accession # P24394-1). | |
| -20°C | |
| IL-4 R alpha | |
| Human | |
| Tris with Glycine, Arginine and NaCl, pH7.5 | |
| HEK293 | |
| Bio-Markers and CD Antigens |