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ACROBiosystems Human Insulin R / CD220 (28-944) Protein, His Tag

SPR verified

Marke:  ACROBiosystems INR-H52Ha-100ug

Weitere Details : Netto-Gewicht : 0.00010kg

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Artikelnummer. 16457779

  • 383.89 € / 100 Mikrogramm
Verfügbar ab: 09-04-2024
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Beschreibung

Beschreibung

Insulin receptor (INSR) is also known as CD antigen CD220, which can be cleaved into the following 2 chains: Insulin receptor subunit alpha and Insulin receptor subunit beta. INSR is a tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains carry the insulin-binding regions, while the beta chains carry the kinase domain. Forms a hybrid receptor with IGF1R, the hybrid is a tetramer consisting of 1 alpha chain and 1 beta chain of INSR and 1 alpha chain and 1 beta chain of IGF1R. In addition to binding insulin, the insulin receptor can bind insulin-like growth factors (IGFI and IGFII). Isoform Short of INSR has a higher affinity for IGFII binding. When present in a hybrid receptor with IGF1R, INSR binds IGF1.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 106.5 kDa. The protein migrates as 115-125 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_000199.2
100 μg
His 28 - Lys 944
INSR,Insulin receptor,IR,CD220
Unconjugated
His Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>90% as determined by SDS-PAGE
106.5 kDa
Human Insulin R (28-944), His Tag (SPR verified) (INR-H52Ha) is expressed from human 293 cells (HEK293). It contains AA His 28 - Lys 944 (Accession # P06213-2).
-20°C
Insulin R
Human
PBS, pH7.4
HEK293
Bio-Markers and CD Antigens
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote