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ACROBiosystems Human Siglec-15 / CD33L3 Protein, Fc Tag

Marke:  ACROBiosystems SG5-H5253-100ug

Weitere Details : Netto-Gewicht : 0.00010kg

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Artikelnummer. 16458029

  • 388.38 € / 100 Mikrogramm

Voraussichtliches Versanddatum: 19-10-2021

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Beschreibung

Beschreibung

Siglec-15 is a DAP12-associated immunoreceptor, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. Siglecs are cell surface proteins that bind sialic acid. They are found primarily on the surface of immune cells and are a subset of the I-type lectins. Siglec-15 consisting of immunoglobulin (Ig)-like domains, transmembrane domain and a short cytoplasmic tail. Siglec-15 is that recognizes sialylated glycans and regulates osteoclast differentiation. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 53.0 kDa. The protein migrates as 55-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_998767.1
HEK293
Human
53.0 kDa
100 µg
Phe 20 - Thr 263
CD33 antigen-like 3,SIGLEC-15,CD33L3,sialic acid-binding Ig-like lectin 15,Siglec15,Siglec-15
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Other Recombinant Proteins
Powder
>95% as determined by SDS-PAGE
Human Siglec-15, Fc Tag (SG5-H5253) is expressed from human 293 cells (HEK293). It contains AA Phe 20 - Thr 263 (Accession # Q6ZMC9-1).
-20°C
Siglec-15
Fc Tag
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Sicherheitsdatenblatt (SDS)
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