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ACROBiosystems Biotinylated Human VSIG3 Protein, Fc, Avitag™
Biotinylated Protein
Marke: ACROBiosystems VS3-H82F9-200ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
VSIG3, also known as IGSF11, BT-IgSF, and CLMP, is a homophilic adhesion molecule that preferentially expressed in the brain. The function of VSIG3 is to stimulate cell growth through homophilic interactions. In clinical, the VSIG3 has been reported to as a novel target for cancer immunotherapy of gastrointestinal and hepatocellular carcinomas. In addition, VSIG-3 is also a ligand of B7 family member VISTA/PD-1H and inhibits human T-cell functions through a novel VSIG-3/VISTA pathway. VSIG-3/VISTA co-inhibitory pathway may provide new strategies for the treatment of human cancers and autoimmune disorders.
This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 51.5 kDa. The protein migrates as 60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| NP_001015887.1 | |
| 200 μg | |
| Leu 23 - Gly 241 | |
| VSIG3,IgSF11,CXADRL1,Bt-IgSF,CT119 | |
| Precision Avi | |
| Fc Tag and Avi Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 51.5 kDa | |
| Biotinylated Human VSIG3, Fc,Avitag (VS3-H82F9) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Gly 241 (Accession # Q5D x 21-1). | |
| -20°C | |
| VSIG3 | |
| Human | |
| Tris with Glycine, Arginine and NaCl, pH7.5 | |
| HEK293 | |
| MABSol™ Biotin Labeled Proteins |