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ACROBiosystems Biotinylated Human ICOS / CD278 (C136S, C137S) Protein, His,Avitag™
Recommended for biopanning
Marke: ACROBiosystems ICS-H82E5-25ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Inducible T-cell costimulator (ICOS) is also known as Activation-inducible lymphocyte immunomediatory molecule (AILIM), CD278, which belongs to the CD28 family of immune costimulatory receptors consisting of CD28, CTLA-4 and PD-1. ICOS enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. CD278 / ICOS prevents the apoptosis of pre-activated T-cells and also plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 17.4 kDa. The protein migrates as 25-32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| NP_036224.1 (C136S, C137S) | |
| 25 μg | |
| Glu 21 - Phe 141 | |
| ICOS,CD278,AILIM,Inducible T-cell costimulator | |
| Precision Avi | |
| His Tag and Avi Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |
| 17.4 kDa | |
| Biotinylated Human ICOS (C136S, C137S), His,Avitag (recommended for biopanning) (ICS-H82E5) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Phe 141 (Accession # Q9Y6W8-1 (C136S, C137S)). | |
| -20°C | |
| ICOS | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| MABSol™ Biotin Labeled Proteins |