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ACROBiosystems Mouse Fc gamma RIV / CD16-2 Protein, His Tag
Marke: ACROBiosystems FC4-M52H3-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
FcgR4(Low affinity immunoglobulin gamma Fc region receptor IV) is also known as CD16-2, FcgammaRIV, receptor for the Fc region of immunoglobulin gamma . Also acts as a receptor for the Fc region of immunoglobulin epsilon . Binds with intermediate affinity to both IgG2a and IgG2b . Does not display binding to IgG1 or IgG3. Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a. Binds with low affinity to both the a and b allotypes of IgE. Has also been shown to bind to IgE allotype a only but not to allotype b. Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 22.8 kDa. The protein migrates as 28-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| NP_653142.2 | |
| 100 μg | |
| Gly 21 - Gln 203 | |
| Fc gamma RIV,CD16-2,Fcgr4 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |
| 22.8 kDa | |
| Mouse CD16-2, His Tag (FC4-M52H3) is expressed from human 293 cells (HEK293). It contains AA Gly 21 - Gln 203 (Accession # A0A0B4J1G0-1). | |
| -20°C | |
| Fc gamma RIV / CD16-2 | |
| Mouse | |
| PBS, pH7.4 | |
| HEK293 | |
| MABSol™ Fc Receptors |