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ACROBiosystems Biotinylated Human LOXL2 Protein, His, Avitag™

Biotinylated Protein

Marke:  ACROBiosystems LO2-H82E3-25ug

Weitere Details : Netto-Gewicht : 0.00010kg

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Artikelnummer. 16477849

  • 419.88 € / 25 Mikrogramm
Verfügbar ab: 09-04-2024
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Beschreibung

Beschreibung

Lysyl oxidase homolog 2 is also known as LOXL2, Lysyl oxidase-like protein 2, which is expressed in many tissues, highest expression in reproductive tissues, placenta, uterus and prostate, Up-regulated in a number of cancers cells and tissues. LOXL2 mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). When secreted in extracellular matrix, promotes cross-linking of extracellular matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. LOXL2 acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding. When nuclear, acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. LOXL2 acts as a regulator of chondrocyte differentiation, probably by regulating expression of factors that control chondrocyte differentiation.

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 87.8 kDa.
Spezifikation

Spezifikation

87.8 kDa
Biotinylated Human LOXL2, His,Avitag (LO2-H82E3) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Gln 774 (Accession # Q9Y4K0-1).
-20°C
LOXL2
Human
HEK293
MABSol™ Biotin Labeled Proteins
25 μg
Gln 26 - Gln 774
Lysyl oxidase homolog 2,LOXL2
Precision Avi
His Tag and Avi Tag
Powder
PBS, pH7.4
Produktvorschläge

Produktvorschläge

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Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote