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ACROBiosystems Human MIS RII Protein, Fc Tag
Marke: ACROBiosystems MII-H5258-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
MIS RII (Mullerian inhibiting substance type II receptor), also known as AMHRII (anti-Mullerian hormone type II receptor), is a serine/threonine receptor with a single transmembrane domain that belongs to the family of type II receptors of the TGF-beta superfamily. Mutations in MIS RII result in persistent Mullerian duct syndrome (PMDS), persistent Müllerian duct syndrome (PMDS) is a sex-limited disorder in which males develop portions of the female reproductive tract. Anti-Müllerian hormone (AMH) and its receptor (AMHR2) induce the regression of the Müllerian ducts in male embryos, but the mechanism by which the Amhr2 gene is specifically activated is not fully understood.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 40.0 kDa. The protein migrates as 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_065434.1 | |
100 μg | |
Pro 18 - Ser 144 | |
MIS RII,MRII,AMHR2,AMHR,MISR2,AMH type II receptor | |
Unconjugated | |
Fc Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
40.0 kDa | |
Human MIS RII, Fc Tag (MII-H5258) is expressed from human 293 cells (HEK293). It contains AA Pro 18 - Ser 144 (Accession # Q16671-1). | |
-20°C | |
MIS RII | |
Human | |
PBS, pH7.4 | |
HEK293 | |
Other Recombinant Proteins |