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ACROBiosystems Human MIS RII Protein, Fc Tag

Marke:  ACROBiosystems MII-H5258-100ug

Weitere Details : Netto-Gewicht : 0.00010kg

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Artikelnummer. 16477869

  • 423.38 € / 100 Mikrogramm
Verfügbar ab: 26-04-2024
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Beschreibung

Beschreibung

MIS RII (Mullerian inhibiting substance type II receptor), also known as AMHRII (anti-Mullerian hormone type II receptor), is a serine/threonine receptor with a single transmembrane domain that belongs to the family of type II receptors of the TGF-beta superfamily. Mutations in MIS RII result in persistent Mullerian duct syndrome (PMDS), persistent Müllerian duct syndrome (PMDS) is a sex-limited disorder in which males develop portions of the female reproductive tract. Anti-Müllerian hormone (AMH) and its receptor (AMHR2) induce the regression of the Müllerian ducts in male embryos, but the mechanism by which the Amhr2 gene is specifically activated is not fully understood.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 40.0 kDa. The protein migrates as 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_065434.1
100 μg
Pro 18 - Ser 144
MIS RII,MRII,AMHR2,AMHR,MISR2,AMH type II receptor
Unconjugated
Fc Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
40.0 kDa
Human MIS RII, Fc Tag (MII-H5258) is expressed from human 293 cells (HEK293). It contains AA Pro 18 - Ser 144 (Accession # Q16671-1).
-20°C
MIS RII
Human
PBS, pH7.4
HEK293
Other Recombinant Proteins
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote