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ACROBiosystems Biotinylated Human Nectin-4 Protein, His, Avitag™
Biotinylated Protein
Marke: ACROBiosystems NE4-H82E7-25ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 37.8 kDa. The protein migrates as 40-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_112178.2 | |
25 μg | |
Gly 32 - Ser 349 | |
NECTIN4,LNIR, PRR4, PVRL4 | |
Precision Avi | |
His Tag and Avi Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
37.8 kDa | |
Biotinylated Human Nectin-4, His,Avitag (NE4-H82E7) is expressed from human 293 cells (HEK293). It contains AA Gly 32 - Ser 349 (Accession # Q96NY8-1). | |
-20°C | |
Nectin-4 | |
Human | |
PBS, pH7.4 | |
HEK293 | |
MABSol™ Biotin Labeled Proteins |