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ACROBiosystems Human Siglec-8 Protein, His Tag

Marke:  ACROBiosystems SI8-H52H8-100ug

Weitere Details : Netto-Gewicht : 0.00010kg

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Artikelnummer. 16488059

  • 353.08 € / 100 Mikrogramm

Voraussichtliches Versanddatum: 30-08-2021

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Beschreibung

Beschreibung

Siglec-8 is also known as SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L and sialic acid binding Ig like lectin 8. Siglec-8 was first identified by CD33 homology screening of ESTs from a cDNA library generated from a patient diagnosed with idiopathic hypereosinophilic syndrome and was originally termed SAF-2 (sialoadhesin family 2). At the tissue level, Siglec-8 mRNA was found to be most highly expressed in lung, PBMCs, spleen, and kidney. Two splice variants of Siglec-8 exist. The initially characterized form contains 431 amino acid residues in total, subsequently, a longer form of Siglec-8, initially termed Siglec-8L. Both forms of Siglec-8 are found in eosinophils and contain a V-set domain with lectin activity and two C2-type Ig repeat domains in the extracellular region.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 39.7 kDa. The protein migrates as 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_002072.2
HEK293
Human
39.7 kDa
100 µg
Met 17 - Ala 363
Siglec-8,SAF-2,SIGLEC8,SAF2
Unconjugated
PBS with Arginine, pH7.4
Less than 1.0 EU / µg by the LAL method.
Other Recombinant Proteins
Powder
>95% as determined by SDS-PAGE
Human Siglec-8, His Tag (SI8-H52H8) is expressed from human 293 cells (HEK293). It contains AA Met 17 - Ala 363 (Accession # Q9NYZ4-1).
-20°C
Siglec-8
His Tag
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate