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ACROBiosystems Human APRIL / TNFSF13 Protein, His Tag
Marke: ACROBiosystems APL-H5244-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
APRIL(a proliferation-inducing ligand) is also known as Tumor necrosis factor ligand superfamily member 13, TALL-2, TRDL-1, CD256, TNFFSF 13, cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. APRIL is a cytokine of the tumor necrosis factor family associated mainly with hematologic malignancies. The closely related TNF family ligands B cell activation factor (BAFF) and a proliferation-inducing ligand (APRIL) serve in the generation and maintenance of mature B-lymphocytes. Both BAFF and APRIL assemble as homotrimers that bind and activate several receptors that they partially share. BAFF-APRIL heteromers of different stoichiometries have distinct receptor-binding properties and activities. In addition, expression of APRIL was regulated by miR-145 in GC cells.
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 22.8 kDa. The protein migrates as 28 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_003799.1 | |
100 µg | |
Ala 105 - Leu 250 | |
APRIL,TNFSF13,TALL-2,TRDL-1,CD256,TALL2,ZTNF2 | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / µg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
22.8 kDa | |
Human APRIL, His Tag (APL-H5244) is expressed from human 293 cells (HEK293). It contains AA Ala 105 - Leu 250 (Accession # O75888-1). | |
-20°C | |
APRIL | |
Human | |
50 mM Tris, 150 mM NaCl, Arginine, pH8.0 | |
HEK293 | |
Bio-Markers and CD Antigens |