missing translation for 'onlineSavingsMsg'
Learn More
Learn More
ACROBiosystems Human / Cynomolgus / Rhesus macaque CD28 Protein, His Tag
MALS verified
Marke: ACROBiosystems CD8-H52Hc-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 17.0 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| NP_006130.1 | |
| 100 μg | |
| Asn 19 - Pro 152 | |
| CD28,Tp44 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |
| 17.0 kDa | |
| Human / Cynomolgus / Rhesus macaque CD28, His Tag (CD8-H52Hc) is expressed from human 293 cells (HEK293). It contains AA Asn 19 - Pro 152 (Accession # P10747-1). In the region Asn 19 - Pro 152, the AA sequence of Human, Cynomolgus and Rhesus macaque CD28 are homologus. | |
| -20°C | |
| CD28 | |
| Human, Cynomolgus Monkey, Rhesus Macaque | |
| PBS, pH7.4 | |
| HEK293 | |
| Immune Checkpoint Proteins |