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ACROBiosystems Biotinylated Human IL-15 R alpha / CD215 Protein, Fc, Avitag™

Biotinylated Protein

Marke:  ACROBiosystems ILA-H82F4-25ug

Weitere Details : Netto-Gewicht : 0.00010kg

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Artikelnummer. 16497729

  • 419.88 € / 25 Mikrogramm
Verfügbar ab: 09-04-2024
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Beschreibung

Beschreibung

IL15R is a heterotrimer of IL15RA, IL2RB and IL2RG. IL-15RA, also known as CD215, IL-15 R alpha, is a widely expressed 60 kDa transmembrane glycoprotein. High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. An interleukin (IL)-15 superagonist/IL-15 receptor α fusion complex (IL-15SA/IL-15RA; ALT-803) activates the IL-15 receptor on CD8 T cells and NK cells, and has shown significant anti-tumor. Signal transduction involves SYK. Higher levels of soluble sIL-15RA form in comparison with membrane-bound forms is present in all brain structures.

This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 46.6 kDa. The protein migrates as 60-75 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_002180.1
25 μg
Ile 31 - Thr 205
IL-15 R alpha,CD215,IL15RA,IL-15 RA,IL-15 R-alpha
Precision Avi
Fc Tag and Avi Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
46.6 kDa
Biotinylated Human IL-15 R alpha, Fc,Avitag (ILA-H82F4) is expressed from human 293 cells (HEK293). It contains AA Ile 31 - Thr 205 (Accession # Q13261-1).
-20°C
IL-15 R alpha
Human
Tris with Glycine, Arginine and NaCl, pH7.5
HEK293
MABSol™ Biotin Labeled Proteins
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote