Learn More
ACROBiosystems Human Properdin Protein, His Tag
Marke: ACROBiosystems PRN-H52H3-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Properdin is also known as Complement factor P, CFP, PFC, a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin is produced by many different leukocyte subsets and circulates as cyclic oligomers of monomeric subunits. Properdin on platelet/granulocyte aggregates(PGA) formation are tightly regulated by Factor H, properdin enhances PGA formation via increased production of C5a, and that inhibition of properdin function has therapeutic potential to limit thromboinflammation in diseases characterized by increased PGA formation.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 50.7 kDa. The protein migrates as 55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_001138724.1 | |
100 μg | |
Asp 28 - Leu 469 | |
Properdin,Complement factor P,CFP,PFC | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>90% as determined by SDS-PAGE |
50.7 kDa | |
Human Properdin, His Tag (PRN-H52H3) is expressed from human 293 cells (HEK293). It contains AA Asp 28 - Leu 469 (Accession # P27918-1). | |
-20°C | |
Properdin | |
Human | |
PBS, pH7.4 | |
HEK293 | |
Other Recombinant Proteins |