missing translation for 'onlineSavingsMsg'
Learn More
Learn More
ACROBiosystems Human TSLP (R127A, R130A) Protein, Mouse IgG2a Fc Tag
Marke: ACROBiosystems TSP-H5255-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine involved in the pathology of inflammatory skin diseases, and is widely expressed by epithelial cells. Human TSLP cDNA encodes a 159 amino acid (aa) residue precursor protein with a 28 aa signal sequence (4, 5). Human TSLP has been shown to developing nondeletional central tolerance, amplifying epithelium-induced class switching, inducing atopic diseases and maintaining intestinal noninflammatory environment. Among diverse cells responding to Human TSLP, CD11c+ dendritic cells are the most obviously characterized target cells.
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 41.6 kDa. The protein migrates as 50-58 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| NP_149024.1 | |
| 100 μg | |
| Tyr 29 - Gln 159 | |
| TSLP | |
| Unconjugated | |
| Mouse IgG Fc Tag | |
| Less than 0.1 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 41.6 kDa | |
| Human TSLP (R127A, R130A), Mouse IgG2a Fc Tag (TSP-H5255) is expressed from human 293 cells (HEK293). It contains AA Tyr 29 - Gln 159 (Accession # Q969D9-1 (R127A, R130A)). | |
| -20°C | |
| TSLP | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Other Recombinant Proteins |