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ACROBiosystems Human NKG2C&CD94 Protein, Fc Tag
Marke: ACROBiosystems NC4-H5258-100UG
Weitere Details : Netto-Gewicht : 0.01000kg
Beschreibung
CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2C/CD159c is used as a receptor for NK cells and some cytotoxic T cells to recognize MHC class I HLA-E molecules. CD94 pairs with the NKG2 molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 57.1 kDa. The protein migrates as 65-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| 57.1 kDa | |
| Human NKG2C&CD94;, Fc Tag (NC4-H5258) is expressed from human 293 cells (HEK293). It contains AA Ile 94 - Leu 231 (NKG2C) and Asp 57 - Ile 179 (CD94) (Accession # P26717-1 (NKG2C) and Q13241-1 (CD94)). | |
| -20°C | |
| NKG2C and CD94 | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Bio-Markers and CD Antigens |
| 100 μg | |
| Ile 94 - Leu 231 (NKG2C) and Asp 57 - Ile 179 (CD94) | |
| NKG2C and CD94 | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |