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  6. 17-(Allylamino)-17-Demethoxygeldanamycin, 99 %, Thermo Scientific Chemicals

17-(Allylamino)-17-Demethoxygeldanamycin, 99 %, Thermo Scientific Chemicals

Catalog Number 15408539
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Menge:
25 mg
100 mg
200 mg
Dieser Artikel kann nicht zurückgegeben werden. Rückgaberichtlinie anzeigen
75747-14-7
C31H43N3O8
585.698
MFCD04973892
AYUNIORJHRXIBJ-MKJFUHJFSA-N
17-aag
133688938
[(3S,5R,6S,7R,8Z,11R,14E)-6-Hydroxy-5,11-dimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-21-(prop-2-enylamino)-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamat
CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)C)OC)OC(=O)N)C)C)O)OC
Dieser Artikel kann nicht zurückgegeben werden. Rückgaberichtlinie anzeigen
75747-14-7
C31H43N3O8
585.698
MFCD04973892
AYUNIORJHRXIBJ-MKJFUHJFSA-N
17-aag
133688938
[(3S,5R,6S,7R,8Z,11R,14E)-6-Hydroxy-5,11-dimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-21-(prop-2-enylamino)-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamat
CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)C)OC)OC(=O)N)C)C)O)OC

Beschreibung

Zeigt Anti-Tumor-Aktivität

17-(Allylamino)-17-demethoxygeldanamycin (17-AAG) inhibits heat shock protein 90 (Hsp90), the expression of heat shock factor-1, and the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2. In addition to its anti-tumor effects, 17-AAG also induces apoptosis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Löslichkeit
Löslich in DMSO bei 150 mg/ml; löslich in Ethanol bei 5 mg/ml. Sehr schlecht wasserlöslich

Hinweise
Nur für Forschungszwecke: Nicht für diagnostische oder therapeutische Zwecke an Tieren und Menschen geeignet.
TRUSTED_SUSTAINABILITY
Chemischer Name oder Material 17-(Allylamino)-17-demethoxygeldanamycin
Schmelzpunkt 207°C to 209°C
Flammpunkt >110°C (230°F)
Menge 200 mg
Empfindlichkeit Light sensitive
Löslichkeitsinformationen Soluble in DMSO at 150mg/mL; soluble in ethanol at 5mg/mL; Very poorly soluble in water
Formelmasse 585.69
Reinheit (%) 99%
Physikalische Form Fest

RUO – Research Use Only

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