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ACROBiosystems Human Complement Factor D / CFD Protein, Fc Tag
Marke: ACROBiosystems CFD-H5256-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Complement factor D (CFD) is also known as Adipsin, C3 convertase activator, Properdin factor D (PFD), which contains one peptidase S1 domain and belongs to the peptidase S1 family. CFD / Adipsin cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. CFD / Adipsin is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Defects in CFD / Adipsin are the cause of complement factor D deficiency which predisposes to invasive meningococcal disease.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.8 kDa. The protein migrates as 53 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| NP_001919.2 | |
| 100 μg | |
| Ile 26 - Ala 253 | |
| CFD,Adipsin,PFD,DF,Complement factor D | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 50.8 kDa | |
| Human Complement Factor D, Fc Tag (CFD-H5256) is expressed from human 293 cells (HEK293) and inactive. It contains AA Ile 26 - Ala 253 (Accession # P00746-1). | |
| -20°C | |
| Complement Factor D | |
| Human | |
| Tris with Glycine, Arginine and NaCl, pH7.5 | |
| HEK293 | |
| Enzymes |