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ACROBiosystems Human HGF Protein, His Tag
MALS verified
Marke: ACROBiosystems HGF-H52H3-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Hepatocyte growth factor (HGF) is a paracrine cellular growth, motility and morphogenic factor. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. In addition, HGF has been implicated in a variety of cancers, including of the lungs, pancreas, thyroid, colon, and breast.
This protein carries a polyhistidine tag at the C-terminus. The mature form of HGF is a disulfide-linked heterodimer composed of proteolytically cleaved α and β chain. The protein has a calculated MW of 81.6 kDa (α chain 53.7 kDa and β chain 27.9 kDa). ThSpezifikation
| 81.6 kDa (53.7 kDa/27.9 kDa) | |
| Human HGF, His Tag (HGF-H52H3) is expressed from human 293 cells (HEK293). It contains AA Gln 32 - Ser 728 (Accession # P14210-1). | |
| -20°C | |
| HGF | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Cytokines and Growth Factors |
| 100 μg | |
| Gln 32 - Ser 728 | |
| HGF,HPTA,SF | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |