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ACROBiosystems Cynomolgus IL-17F Protein, His Tag
Marke: ACROBiosystems ILF-C5243-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Interleukin-17F (IL17F) is also known as Interleukin-24 (IL24), Cytokine ML-1, is a secreted disulfide-linked homodimer which belongs to the IL-17 family. There are at least six members of the IL-17 family in humans and in mice: IL-17A, IL-17B, IL-17C, IL-17D, IL-17E (also called IL-25) and IL-17F (also called IL-24). IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. IL-17F / IL-24 is expressed in activated, but not resting, CD4+ T-cells and activated monocytes. IL17F / Interleukin-24 stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. IL17F / IL-24 stimulates PBMC and T-cell proliferation and Inhibits angiogenesis. Defects in IL17F are the cause of familial candidiasis type 6 (CANDF6).
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 16.8 kDa. The protein migrates as 22-25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| XP_005552814.1 | |
| 100 μg | |
| Arg 31 - Gln 163 | |
| IL-17 F,Interleukin-17 F,Cytokine ML-1 | |
| Unconjugated | |
| His Tag | |
| Less than 0.1 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 16.8 kDa | |
| Cynomolgus IL-17 F, His Tag (ILF-C5243) is expressed from human 293 cells (HEK293). It contains AA Arg 31 - Gln 163 (Accession # G7P4V0-1). | |
| -20°C | |
| IL-17 F | |
| Cynomolgus Monkey | |
| PBS, pH7.4 | |
| HEK293 | |
| Cytokines and Growth Factors |