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ACROBiosystems Human Nectin-4 Protein, Fc Tag

Marke:  ACROBiosystems NE4-H5255-100ug

Weitere Details : Netto-Gewicht : 0.00010kg

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Artikelnummer. 17146531

  • 419.88 € / 100 Mikrogramm
Verfügbar ab: 09-04-2024
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Beschreibung

Beschreibung

Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 60.5 kDa. The protein migrates as 65-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_112178.2
100 μg
Gly 32 - Ser 349
NECTIN4,LNIR, PRR4, PVRL4
Unconjugated
Fc Tag
Less than 0.1 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
60.5 kDa
Human Nectin-4, Fc Tag (NE4-H5255) is expressed from human 293 cells (HEK293). It contains AA Gly 32 - Ser 349 (Accession # Q96NY8-1).
-20°C
Nectin-4
Human
Tris with Glycine, Arginine and NaCl, pH7.5
HEK293
Immune Checkpoint Proteins
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote