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ACROBiosystems FITC-Labeled Human CD30 / TNFRSF8 Protein, Fc Tag
Marke: ACROBiosystems CD0-HF250-200ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF-8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 64.6 kDa. The protein migrates as 70-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_001234.2 | |
200 μg | |
Phe 19 - Lys 379 | |
TNFRSF8,CD30,D1S166E,Ki-1 | |
FITC | |
Fc Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>90% as determined by SDS-PAGE |
64.6 kDa | |
FITC-Labeled Human CD30, His Tag (Cat. No. CD0-HF250) is expressed from human HEK293 cells. It contains AA Phe 19 - Lys 379 (Accession # NP_001234.2). It is the FITC labeled form of Human CD30, His Tag (Cat. No.CD0-H5250). | |
-20°C | |
CD30 | |
Human | |
PBS, pH7.4 | |
HEK293 | |
Bio-Markers and CD Antigens |