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ACROBiosystems Biotinylated Mouse CD28 Protein, His, Avitag™
Biotinylated Protein
Marke: ACROBiosystems CD8-M82E3-200ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
CD28 homolog (CD28H), also called transmembrane and immunoglobulin domain containing 2 (TMIGD2) and IGPR-1,is encoded by the TMIGD2 gene. CD28H is constitutively expressed on naive T and NK cells. After interaction of CD28 homolog with B7 homologue,the peripheral effector and memory T cells can be activated and proliferated by Akt-dependent signalling cascade. Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 18.6 kDa. The protein migrates as 30-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| NP_031668.3 | |
| 200 μg | |
| Asn 20 - Lys 149 | |
| CD28,Tp44 | |
| Precision Avi | |
| His Tag and Avi Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |
| 18.6 kDa | |
| Biotinylated Mouse CD28, His,Avitag (CD8-M82E3) is expressed from human 293 cells (HEK293). It contains AA Asn 20 - Lys 149 (Accession # P31041-1). | |
| -20°C | |
| CD28 | |
| Mouse | |
| PBS, pH7.4 | |
| HEK293 | |
| MABSol™ Biotin Labeled Proteins |