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ACROBiosystems Human MICA Protein, Fc Tag
MALS verified
Marke: ACROBiosystems MIA-H5253-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
MHC class I polypeptide-related sequence A (MICA) belongs to the MHC class I family and MIC subfamily. MICA contains one Ig-like C1-type (immunoglobulin-like) domain. Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta-2-microglobulin. MICA acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. MICA is ligand for the KLRK1/NKG2D receptor. MICA bind to KLRK1 leads to cell lysis.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 59.3 kDa. The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.Spezifikation
| AAH16929.1 | |
| 100 μg | |
| Glu 24- Gln 308 | |
| MIC-A | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 59.3 kDa | |
| Human MICA, Fc Tag (MALS verified) (MIA-H5253) is expressed from human 293 cells (HEK293). It contains AA Glu 24- Gln 308 (Accession # AAH16929.1). | |
| -20°C | |
| MICA | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Other Recombinant Proteins |