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ACROBiosystems Mouse TROP-2 / TACSTD2 Protein, His Tag
Marke: ACROBiosystems TR2-M52H6-1mg
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
TROP-2 is a single-copy gene in human cells, and encodes a type-1 transmembrane glycoprotein which is over-expressed in various malignancies, also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1. TROP-2 is related to epithelial cell adhesion molecule (EpCAM), also called TROP-1, gp40, and KSA. Trop-1 and Trop-2 are homologous to serum IGF-II-binding proteins and appear as signal transducers. Thus, they likely represent novel cell-surface receptors and may play a role in regulating the growth of carcinoma cells.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 29.9 kDa. The protein migrates as 38-48 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.Spezifikation
| NP_064431.2 | |
| 1 mg | |
| Gln 25 - Gly 270 | |
| TACSTD2,GA733-1,M1S1,TROP2 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |
| 29.9 kDa | |
| Mouse TROP-2, His Tag (TR2-M52H6) is expressed from human 293 cells (HEK293). It contains AA Gln 25 - Gly 270 (Accession # Q8BGV3-1). | |
| -20°C | |
| TROP-2 | |
| Mouse | |
| PBS, pH7.4 | |
| HEK293 | |
| Other Recombinant Proteins |