missing translation for 'onlineSavingsMsg'
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ACROBiosystems Human Kremen-1 protein, Fc Tag
Marke: ACROBiosystems KR1-H5253-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Kremens are high-affinity receptors for Dickkopf 1 (Dkk1) and regulate the Wnt/β-catenin signaling pathway by down-regulating the low-density lipoprotein receptor-related protein 6 (LRP6). Kremen1 is considered as one component of a membrane complex modulating canonical Wnt signalling through LRP6 in vertebrates. Additionally, KREMEN1 (KRM1) has also been identified as a functional receptor for Coxsackievirus A10 (CV-A10), a causative agent of hand-foot-and-mouth disease (HFMD).
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 67.4 kDa. The protein migrates as 80-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| 67.4 kDa | |
| Human Kremen-1, Fc Tag (KR1-H5253) is expressed from human 293 cells (HEK293). It contains AA Arg 21 - Thr 392 (Accession # Q96MU8-1). | |
| -20°C | |
| KREMEN1 | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Other Recombinant Proteins |
| 100 μg | |
| Arg 21 - Thr 392 | |
| KREMEN, KRM1,Dickkopf receptor/Kringle domain-containing transmembrane protein 1/Kringle-containing protein marking the eye and the nose | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |