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ACROBiosystems MERS Nucleocapsid protein, His Tag
Marke: ACROBiosystems NUN-M52H5-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.
This protein carries a polyhistidine tag at the C-terminus. This protein contains a furin cleavage site, 251-RHKR-254, and is partially processed into N and C-terminal fragment with calculated MW of 17.1 kDa and 19.7 kDa respectively. The protein migratesSpezifikation
| 46.7 kDa | |
| MERS Nucleocapsid protein, His Tag (NUN-M52H5) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Asp 413 (Accession # K0BVN3-1). | |
| -20°C | |
| Nucleocapsid protein | |
| MERS‐CoV | |
| PBS, pH7.4 | |
| HEK293 | |
| Viral Proteins |
| 100 μg | |
| Met 1 - Asp 413 | |
| Nucleocapsid protein,NP,Protein N,COVID-19 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |