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  6. 4-(2-Aminoethyl)Benzolsulfonylfluoridhydrochlorid, 97 %, Thermo Scientific Chemicals

4-(2-Aminoethyl)Benzolsulfonylfluoridhydrochlorid, 97 %, Thermo Scientific Chemicals

Catalog Number p-7029041
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Menge:
250 mg
1 g
30827-99-7
C8H11ClFNO2S
239.689
MFCD00132962
WRDABNWSWOHGMS-UHFFFAOYSA-N
4-2-aminoethyl benzenesulfonyl fluoride hydrochloride, aebsf, aebsf hydrochloride, pefabloc sc, aebsf hcl, pefabloc, 4-2-aminoethyl benzene-1-sulfonyl fluoride hydrochloride, aebsf, hydrochloride, benzenesulfonyl fluoride, 4-2-aminoethyl-, hydrochloride, 4-2-aminoethyl benzenesulfonylfluoride hydrochloride
186136
4-(2-aminoethyl)benzolesulfonylfluorid;Hydrochlorid
C1=CC(=CC=C1CCN)S(=O)(=O)F.Cl
30827-99-7
C8H11ClFNO2S
239.689
MFCD00132962
WRDABNWSWOHGMS-UHFFFAOYSA-N
4-2-aminoethyl benzenesulfonyl fluoride hydrochloride, aebsf, aebsf hydrochloride, pefabloc sc, aebsf hcl, pefabloc, 4-2-aminoethyl benzene-1-sulfonyl fluoride hydrochloride, aebsf, hydrochloride, benzenesulfonyl fluoride, 4-2-aminoethyl-, hydrochloride, 4-2-aminoethyl benzenesulfonylfluoride hydrochloride
186136
4-(2-aminoethyl)benzolesulfonylfluorid;Hydrochlorid
C1=CC(=CC=C1CCN)S(=O)(=O)F.Cl

Beschreibung

AEBSF is extensively used in studies aiming to describe cholesterol regulatory genes due to its potent ability to inhibit Site-1-protease (S1P). This serine protease, located in the Golgi apparatus, is responsible for activating the sterol regulatory element-binding proteins. By selectively inhibiting S1P, AEBSF can be used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Anwendungen
AEBSF is extensively used in studies aiming to describe cholesterol regulatory genes due to its potent ability to inhibit Site-1-protease (S1P). Diese Serinprotease, die sich im Golgi-Apparat befindet, ist für die Aktivierung der sterinregulierenden Elementbindungs-Proteine verantwortlich. Durch die selektive Hemmung von S1P kann AEBSF verwendet werden, um das Folgeergebnis der SREBP-Hemmung und ihren Einfluss auf die Cholesterinregulation zu charakterisieren.

Löslichkeit
Löslich in Wasser 50 mg/ml oder 100 % Ethanol.

Hinweise
Feuchtigkeitsempfindlich. Kühl lagern. Behälter an einem trockenen und gut belüfteten Ort dicht verschlossen halten. Von starken Oxidationsmitteln, Luft und Feuchtigkeit fernhalten.
TRUSTED_SUSTAINABILITY
Chemischer Name oder Material 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride
Schmelzpunkt ∼184°C (decomposition)
Menge 250 mg
UN-Nummer UN3261
Beilstein 7604627
Empfindlichkeit Moisture sensitive
Löslichkeitsinformationen Soluble in water 50mg/mL or 100% ethanol.
Formelmasse 239.69
Reinheit (%) 97%

RUO – Research Use Only

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