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A 83-01, MedChemExpress

Product Code. 16463968
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Product Code. 16463968 Supplier Medchem Express Supplier No. HY10432
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Verfügbar ab: 01-12-2026
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Description

MedChemExpress A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase, type I nodal receptor ALK4 and type I nodal receptor ALK7, with IC50s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5, ALK4 and ALK7, respectively.

A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase, type I nodal receptor ALK4 and type I nodal receptor ALK7, with IC50s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5, ALK4 and ALK7, respectively.

Specifications

Chemical Name or Material A 83-01
CAS 909910-43-6
Color Off-White
Purity Grade Notes Research
Molecular Formula C25H19N5S
Quantity 10 mg
Solubility Information DMSO : 25 mg/mL (59.31 mM; ultrasonic and warming and heat to 60°C) ∣H2O : < 0.1 mg/mL (insoluble)
SMILES S=C(N1N=C(C2=NC(C)=CC=C2)C(C3=CC=NC4=CC=CC=C34)=C1)NC5=CC=CC=C5
Molecular Weight (g/mol) 421.52
Formula Weight 421.52
Percent Purity 95.0%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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