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Invitrogen™ ACSL6 Polyclonal Antibody
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Artikelnummer. 13494957
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Menge:
100 μL
Packungsgröße:
100 Mikroliter
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Artikelnummer. Menge unitSize
13494957 100 μL 100 Mikroliter
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Artikelnummer. 13494957 Lieferant Invitrogen™ Lieferanten-Nr. PA530465

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Beschreibung

Rabbit Polyclonal Antibody

Recommended positive controls: Jurkat, Raji, K562, THP-1, NCI-H929, mouse heart, rat heart. Predicted reactivity: Mouse (91%), Rat (89%), Rabbit (92%), Chimpanzee (100%), Bovine (93%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

FACL6 is involved in activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. It plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid. FACL6 is expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derieved from fetal liver, haemopoietic stem cells from cord blood, bone marrow, and brain. Expression is low at earlier stages of erythroid development but is very high in reticulocytes. This protein is involved in myelodysplastic syndrome (MDS) with basophilia, acute myelogenous leukemia (AML) with eosinophilia, and acute eosinophilic leukemia (AEL). It is characterized by a chromosomal translocation t(5;12)(q31;p13) that involves ETV6 and ACSL6.
TRUSTED_SUSTAINABILITY

Spezifikation

Antigen ACSL6
Anwendungen Western Blot
Klassifikation Polyclonal
Konzentration 1 mg/mL
Konjugat Unconjugated
Zusammensetzung 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gen Acsl6
Gen-Zugriffsnummer P33124, Q91WC3, Q9UKU0
Gen-Alias A330035H04Rik; ACS2; ACSL6; acyl-CoA synthetase long-chain family member 6; Arachidonate--CoA ligase; AW050338; FACL6; fatty acid Coenzyme A ligase, long chain 6; fatty-acid-Coenzyme A ligase, long-chain 6; KIAA0837; L LACS5; LACS; LACS 6; LACS2; LACS5; Lacsl; long fatty acyl-CoA synthetase 2; long-chain acyl-CoA synthetase 6; Long-chain-fatty-acid--CoA ligase 6; long-chain-fatty-acid--CoA ligase, brain isozyme; mKIAA0837
Gensymbole Acsl6
Wirtsspezies Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human ACSL6. The exact sequence is proprietary.
Reinigungsverfahren Antigen affinity chromatography
Menge 100 μL
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 117243, 216739, 23305
Zielspezies Human, Mouse, Rat
Inhalt und Lagerung Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttyp Antibody
Form Liquid
Isotype IgG
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