Tocris Bioscience™ AEG 40730 dihydrochloride

Name: Tocris Bioscience&trade; AEG 40730 dihydrochloride
SKU: p-5545520

IAP antagonist; induces apoptosis

N.V.

Beschreibung

IAP antagonist; binds to the BIR3 domain of cIAP1, cIAP2 and XIAP with nanomolar affinity. Reduces cIAP1, cIAP2 and XIAP protein levels in human breast cancer MDA-MB-231 cells. Induces apoptosis in combination with TNF, and potentiates TRAIL-mediated apoptosis in human colorectal carcinoma HCT 116 cells. Cell permeable.

For Research Use Only

Zurück zum Seitenanfang

Tocris Bioscience™ AEG 40730 dihydrochloride

Beschreibung

Dokumentation