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CD11b Mouse anti-Rat, FITC, Clone: WT.5, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 561684

Weitere Details : Netto-Gewicht : 0.01000kg

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Artikelnummer. 15891229

  • 191.52 € / 1 Stück
Verfügbar ab: 23-12-2022
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Beschreibung

Beschreibung

The WT.5 monoclonal antibody specifically binds to CD11b, the α subunit of Mac-1 found on neutrophils and myeloid cells, but not on lymphocytes. Mac-1 expression is rapidly upregulated on neutrophils after activation, in the same time period that CD62L (L-selectin) is shed from the cell surface. Mac-1 mediates adhesion to ICAM-1 (CD54) and C3bi. Neutrophil binding to ICAM-1 is blocked by mAb WT.5.

This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Spezifikation

Spezifikation

CD11b
Monoclonal
0.5mg/mL
Itgam; Integrin αM chain; Mac-1 α chain; Integrin beta 2 alpha subunit
Mouse
Affinity Purified
RUO
Rat
IgA κ
Flow Cytometry
WT.5
FITC
Aqueous buffered solution containing ≤0.09% sodium azide.
Rt neutrophils
50 μg
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote

For Research Use Only.