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CD11b/Mac-1 Mouse anti-Human, PE-Cy7, Clone: ICRF44, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 561685

Weitere Details : Netto-Gewicht : 0.01000kg

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Artikelnummer. 15801239

  • 212.00 € / 1 Stück

Verfügbar ab
07-10-2020

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Beschreibung

Beschreibung

The ICRF44 monoclonal antibody specifically binds to CD11b, the 165-kDa adhesion glycoprotein that associates with the 95-kDa integrin β2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3. CD11b is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3). This antibody significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP.

Spezifikation

Spezifikation

CD11b
ICRF44
Mac-1α, integrin αM subunit, CR3 α chain
Affinity Purified
Human monocytes
25 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
PE-Cyanine7
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
IgG1, κ
RUO
Primary
Human
Videos
Dokumentation

For Research Use Only.