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CD11b/Mac-1 Mouse anti-Human, PE-Cy7, Clone: ICRF44, BD
Mouse Monoclonal Antibody
Marke: BD Biosciences 561685
Weitere Details : Netto-Gewicht : 0.01000kg
Beschreibung
The ICRF44 monoclonal antibody specifically binds to CD11b, the 165-kDa adhesion glycoprotein that associates with the 95-kDa integrin β2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3. CD11b is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3). This antibody significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP.
Spezifikation
CD11b | |
Monoclonal | |
PE-Cyanine7 | |
Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
Human monocytes | |
25 Tests | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
Flow Cytometry | |
ICRF44 | |
Mac-1α, integrin αM subunit, CR3 α chain | |
Mouse | |
Affinity Purified | |
RUO | |
Human | |
IgG1 κ |
For Research Use Only.