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CD14 Mouse anti-Human, Brilliant Violet 650, Clone: M5E2, BD
Mouse Monoclonal Antibody
Marke: BD Biosciences 563419
Weitere Details : Netto-Gewicht : 0.01000kg
Beschreibung
The M5E2 monoclonal antibody specifically binds to CD14, a 53–55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein expressed at high levels on monocytes. Additionally, the anti-CD14 antibody reacts with interfollicular macrophages, reticular dendritic cells, and some Langerhans cells. CD14 has been identified as a high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS) and serum LPS-binding protein, LPB.
The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon™ Brilliant Violet™ family of dyes. This dye is a tandem fluorochrome of BD Horizon™ BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 650-nm. BD Horizon™ BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20-nm filter). Due to the excitation and emission characteristics of the acceptor dye, there will bespillover into the APC and Alexa Fluor™ 700 detectors. However, the spillover can be corrected through compensation as with any other dye combination.
Spezifikation
| CD14 | |
| Monoclonal | |
| Brilliant Violet 650 | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Human CD14 Protein | |
| 100 Tests | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| M5E2 | |
| LPS receptor; LPS-R; Myeloid cell-specific leucine-rich glycoprotein | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Baboon, Canine, Cynomolgus, Human, Rhesus Monkey | |
| IgG2a κ |
For Research Use Only.