CD184 Mouse anti-Human, APC, Clone: 12G5, BD
Mouse Monoclonal Antibody
Marke: BD Biosciences 560936
Weitere Details : Netto-Gewicht : 0.01000kg
Reacts with fusin (CXCR4), a seven-transmembrane domain, G-protein-linked glycoprotein. Fusin is expressed on a wide variety of CD4+ and CD4- cells including those from spleen, brain and lung. It has been shown to function as a cofactor for infection with T-cell tropic strains of HIV-1 and also as a receptor for CD4-independent infection. 12G5 antibody has been reported to block CD4-independent infection by HIV-2 and CD4-dependent infection by some T-cell tropic isolates of HIV-1.
Host Species: Mouse
Isotype: IgG2a κ
Species Reactivity: Human
|CXCR4; Fusin; SDF-1 receptor; LAP3; LCR1; LESTR; NPYY3R; NPY3R; WHIM; HM89|
|SIVmac variant CP-MAC-infected Sup-T1 cells|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
For Research Use Only.