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CD42b Mouse anti-Human, FITC, Clone: HIP1, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 561855

Weitere Details : Netto-Gewicht : 0.02000kg

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Artikelnummer. 15801409

  • 169.00 € / 1 Stück

Verfügbar ab
14-10-2020

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Beschreibung

Beschreibung

The HIP1 monoclonal antibody specifically binds to CD42b. CD42b is also known as the Platelet glycoprotein Ib alpha chain that is encoded by the GP1BA gene. CD42b is disulfide bonded to CD42c to form a 170 kDa heterodimer, GPIb. GPIb forms a noncovalent complex with CD42a and CD42d (CD42 complex) that is expressed on platelets and megakaryocytes. The CD42 complex serves as the von Willebrand Factor(vWF) surface receptor involved in the adhesion of platelets to the subendothelium of damaged vascular walls. HIP1 inhibits the ristocetin-dependent binding ofvWF to platelets and partially inhibits collagen-induced aggregation.

Spezifikation

Spezifikation

CD42b
HIP1
GP1BA; GPIbalpha; GP-Ib alpha; GPIb-alpha; CD42b-alpha; Glycocalicin; BSS
Affinity Purified
IgG1, κ
RUO
Primary
Human
Flow Cytometry
FITC
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
25 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Videos
Dokumentation

For Research Use Only.