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CD8 Mouse anti-Human, APC-H7, Clone: SK1, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 560179

Weitere Details : Netto-Gewicht : 0.01000kg

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Artikelnummer. 15879988

  • 547.20 € / 1 Stück
Verfügbar ab: 19-12-2022
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Beschreibung

Beschreibung

CD8 recognizes the 32kDa a-subunit of a disulfide-linked bimolecular complex. The majority of peripheral blood CD8+ T lymphocytes express an a/b heterodimer (Mr 32, 30kDa), while CD8+CD16+ natural killer (NK) lymphocytes and CD8+ T-cell receptor (TCR)-γ/δ+ lymphocytes express a/a homodimer (Mr 30kDa). CD8+TCR-α/β+ lymphocytes can express either an α/α homodimer or α/β heterodimer. The CD8 antigenic determinant binds to class I major histocompatibility (MHC) molecules resulting in increased adhesion between the CD8+ T lymphocytes and target cells. Binding of the CD8 antigen is coupled to a protein tyrosine kinase p56lck. The CD8:p56lck complex can play a role in T-lymphocyte activation through mediation of the interactions between the CD8 antigen and the CD3/TCR complex.

Host Species: Mouse
Clone: SK1
Isotype: IgG1 κ
Species Reactivity: Human
Immunogen: Human Peripheral Blood T Cells

Flow Cytometry

Spezifikation

Spezifikation

CD8
Monoclonal
APC-H7
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Human Peripheral Blood T Cells
100 Tests
Immunology
Rhesus Monkey, Human, Cynomolgus, Baboon
IgG1 κ
Flow Cytometry
SK1
CD8α; CD8A; CD8 alpha; Leu2a; MAL; T8; p32
Mouse
Affinity Purified
RUO
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote

For Research Use Only.