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CD86 Mouse anti-Human, PE, Clone: 2331 (FUN-1), BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 560957

Weitere Details : Netto-Gewicht : 0.01000kg

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Artikelnummer. 15800639

  • 142.00 € / 1 Stück

Verfügbar ab
14-10-2020

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Beschreibung

Beschreibung

The 2331 (FUN-1) monoclonal antibody specifically recognizes a 75 kDa transmembrane cell surface protein, CD86 (B70/B7-2), expressed primarily on monocytes, dendritic cells and activated B cells. Competitive binding assays demonstrate that, while both 2331 (FUN-1) and IT2.2 (anti-CD86, Cat. No. 555663) antibodies specifically recognize the same molecule, they react with different epitopes. CD86 is the second ligand for CD28 and CTLA-4 and may play an important role in co-stimulation of T cells in primary immune response. The 2331 (FUN-1) antibody blocks the costimulatory activity of CD86 when tested in functional studies.

This antibody is routinely tested on Daudi cells by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Spezifikation

Spezifikation

CD86
2331 (FUN-1)
B7.2; B7-2; B-lymphocyte activation antigen B7-2; B70; BU63; CD28LG2; LAB72
Affinity Purified
Human HBL-1 Cell Line
25 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
PE
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
IgG1, κ
RUO
Primary
Human
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Dokumentation

For Research Use Only.