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Heme Oxygenase 1 Mouse anti-Human, Unlabeled, Clone: 23, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 610713

Weitere Details : Netto-Gewicht : 0.01000kg

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Artikelnummer. 15885599

  • 605.34 € / 1 Set
Verfügbar ab: 03-01-2023
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Beschreibung

Beschreibung

Heme oxygenases 1 and 2 (HO-1, HO-2) cleave the heme molecule, resulting in the production of carbon monoxide (CO) and biliverdin. HO-1 is a 288 amino acid monooxygenase with a molecular weight of 32kDa. While HO-2 is constitutively expressed in tissues, HO-1 is rapidly induced by several stimuli such as lutathione depletion, hemin, heat shock, heavy metals, oxidative stress, oxidized LDL, anoxia, and endotoxic shock. Similar to nitric oxide (NO), CO activates guanylate cyclase and reduces platelet aggregation. Several conditions that increase NO also induce HO-1 expression and activity. This suggests that NO synthases, Cox-2, and HO-1 are part of a general defense mechanism against stress and pathogen invasion.

Immunofluorescence, Immunoprecipitation, Western Blotting

Spezifikation

Spezifikation

Heme Oxygenase 1
Monoclonal
250μg/mL
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Human Heme Oxygenase 1 (HO-1) aa. 150-286
150 μg
Cell Biology
Human
IgG1
Western Blot
23
Unconjugated
Mouse
Affinity Purified
RUO
Primary
Store undiluted at -20°C.
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote

For Research Use Only.