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Huntingtin Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Invitrogen PA1003
Weitere Details : Netto-Gewicht : 0.10000kg
Beschreibung
Neoepitope antibodies distinguish smaller cleaved fragments or processed forms of proteins versus the intact full-length or precursor by using a designed peptide purification process to maximize immunoreactivity to a specific cleavage site. Human HTT caspase cleavage sites generate fragment-specific forms of the protein. Caspase-3/7 has been shown to generate cleavage sites at animo acids 513 and 552. Caspase-2 cleaves at amino acid 552 and caspase-6 at amino acid 586. Neo-specific antibody PA1-003 recognizes the 552 cleaved fragment without detecting the full-length form.
Huntingtin Polyclonal antibody specifically detects Huntingtin in Human, Mouse samples. It is validated for ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot.Spezifikation
| Huntingtin | |
| Polyclonal | |
| Unconjugated | |
| Htt | |
| AI256365; C430023I11Rik; Hd; HD protein; HD protein homolog; Hdh; HTT; Huntingtin; huntingtin (Huntington disease); Huntingtin, myristoylated N-terminal fragment; Huntington disease gene homolog; huntington disease protein; huntington disease protein homolog; IT15; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 15194, 3064 | |
| -20°C | |
| Liquid |
| ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot | |
| 0.4 mg/mL | |
| PBS with 1mg/mL BSA and 0.05% sodium azide | |
| P42858, P42859 | |
| Htt | |
| Synthetic peptide conjugated to KLH via cysteine corresponding to residues SDPAMDLND (544-552) of Human HTT. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |