KGF Polyclonal Antibody, Invitrogen™

Beschreibung

PA1-32177 detects KGF from human samples. PA1-32177 has been successfully used in Western blot and ELISA applications. The PA1-32177 immunogen is recombit hKGF (human Keratinocyte Growth Factor).

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predomitly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.