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Ku80 Rabbit anti-Human, Non-human primate, Polyclonal, Invitrogen

Rabbit Polyclonal Antibody

Marke:  Invitrogen PA532472

Weitere Details : Netto-Gewicht : 0.01000kg

Artikelnummer. 13486987

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Beschreibung

Beschreibung

Heat-mediated antigen retrieval is recommended prior to staining, using a 1mM EDTA buffer, pH 8.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is placenta tissue.

X-ray repair cross-complementing protein 5 (XRCC5), alternative name (Ku80), is a single stranded DNA-dependent ATP-dependent helicase. It is involved in chromosome translocation. Ku80 along with Ku70 forms a heterodimeric protein originally identified as autoantigens, associated with several autoimmune diseases including scleroderma, polymyositis and systemic lupus erythematosus. Ku is a widely expressed nuclear protein that binds to and stabilizes the ends of DNA at telomeres or double-stranded DNA breaks. The inhibition of Ku80 can damage the DNA repair pathway of tumor cells and potentially increase the killing of cancer cells.
Spezifikation

Spezifikation

Ku80
Polyclonal
XRCC5
KARP-1, KARP1, KU80, KUB2, Ku86, NFIV, 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 80 kDa subunit, CTC box-binding factor 85 kDa subunit, CTC85, CTCBF, DNA repair protein XRCC5, Ku autoantigen, 80kDa, Ku86 autoantigen related protein 1, TLAA, X-ray
Rabbit
Antigen affinity chromatography
RUO
7520
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
P13010
XRCC5
Synthetic peptide derived from the C-terminus of human Ku80 protein
500 μL
Primary
Human, Non-human Primate
Antibody
IgG
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote