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L3MBTL1 Mouse anti-Human, Clone:, Invitrogen™
Mouse Monoclonal Antibody
Marke: Invitrogen 730022
Weitere Details : Netto-Gewicht : 0.01000kg
Beschreibung
L3MBTL1 is the homolog of a protein identified in Drosophila as a suppressor of maligt transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. L3MBTL1 is localized to condensed chromosomes in mitotic cells and overexpression of this protein in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells. L3MBTL1 represents a polycomb group gene the encoded protein functions to regulate gene activity, likely via chromatin modification. Polycomb group protein specifically recognizes and binds mono- and dimethyllysine residues on target proteins, thereby acting as a reader of a network of post-translational modifications. Alternatively spliced transcript variants encoding different isoforms of the L3MBTL1 gene have been identified.Spezifikation
L3MBTL1 | |
Monoclonal | |
Unconjugated | |
Q9Y468 | |
L3MBTL1 | |
200-530 of 772 of L3MBTL1 Protein. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
Immunoprecipitation | |
0.5 mg/mL | |
L3MBTL1 | |
H-L(3)MBT, L3MBTL, dJ138B7.3, l(3)mbt protein homolog, lethal (3) maligt brain tumor l(3), lethal(3)maligt brain tumor-like protein 1 | |
Mouse | |
Affinity chromatography | |
RUO | |
26013 | |
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C | |
Liquid |