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Nek2 Mouse anti-Human, Unlabeled, Clone: 20, BD
Mouse Monoclonal Antibody
330.00 € - 650.00 €
Spezifikation
| Antigen | Nek2 |
|---|---|
| Klon | 20 |
| Konzentration | 250μg/mL |
| Anwendungen | Western Blot |
| Klassifikation | Monoclonal |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
15885529
|
BD Biosciences
610593 |
50 μg |
330.00 €
1 Set |
Verfügbar ab: 16-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
|
15895529
|
BD Biosciences
610594 |
150 μg |
650.00 €
1 Set |
Verfügbar ab: 16-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
Beschreibung
Reversible protein phosphorylation is critical for progression through the cell cycle and mitosis. In Aspergillus nidulans, the nima gene (neveritosis) encodes a protein kinase that is essential for mitosis. Three human genes (nek1, 2, and 3 [Nima-related kinase]) with significant homology to the A. nidulans nima have been reported. The nek2 gene encodes a protein of 445 amino acids and, like its fungal homolog, its expression is regulated throughout the cell cycle. In Hela cells, Nek2 activity and expression are low during M and G1 phases of the cell cycle. However, both parameters increase during S phase and mitosis. In addition, Nek2 phosphorylates protein substrates exclusively at serine and threonine residues. Thus, like its fungal homolog, Nek2 may be a crucial element in controlling the cell's entry into S phase and mitosis.
This antibody is routinely tested by western blot analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Spezifikation
| Nek2 | |
| 250μg/mL | |
| Monoclonal | |
| Mouse | |
| Cell Biology | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| IgG1 | |
| Affinity Purified | |
| Nima Related Kinase 2 |
| 20 | |
| Western Blot | |
| Unconjugated | |
| RUO | |
| Human | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| Primary | |
| Store undiluted at -20°C. |
For Research Use Only.