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Phospho-LKB1 (Ser428) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Marke:  Invitrogen PA538366

Weitere Details : Netto-Gewicht : 0.00900kg

Artikelnummer. 15535291

  • 451.00 € / 100 Mikrogramm
Verfügbar ab: 06-05-2024
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Beschreibung

Beschreibung

LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11), a member of the serine/threonine kinase family, is a tumor suppressor. LKB1 physically associates with p53 and regulates specific p53 dependent apoptosis pathways. LKB1 is present in both the cytoplasm and nucleus of living cells and translocates to mitochondria during apoptosis. LKB1 functions as a master upstream protein kinase, regulating AMPK related kinases as well as AMPK. Mutations in LKB1 gene are associated with Peutz Jeghers syndrome.
Spezifikation

Spezifikation

Phospho-LKB1 (Ser428)
Polyclonal
Unconjugated
STK11
Serine/threonine-protein kinase STK11, Liver kinase B1, LKB1, hLKB1, Renal carcinoma antigen NY-REN-19, STK11, LKB1, PJS
Rabbit
Antigen affinity chromatography
RUO
20869, 6794
-20°C
Liquid
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Q15831, Q9WTK7
STK11
A synthetic phosphopeptide derived from human LKB1 around the phosphorylation site of Ser428 (R-L-SP-A-C)
100 μg
Primary
Human, Mouse
Antibody
IgG
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote